Identification | More | [Name]
Zinc acetate dihydrate | [CAS]
5970-45-6 | [Synonyms]
ACETIC ACID ZINC SALT ACETIC ACID ZINC SALT DIHYDRATE ZINC ACETATE ZINC ACETATE 2H2O ZINC ACETATE-2-HYDRATE ZINC ACETATE DIHYDRATE ZINC ACETATE HYDRATE ZINC ACETATE, HYDROUS Octan zinecnaty octanzinecnaty Zinc diacetate, dihydrate zincdiacetate,dihydrate Acetoxyzinc ZINC ACETATE DIHYDRATE, ACS ZINC ACETATE DIHYDRATE, 98+%, A.C.S. REA GENT Zinc acetate dihydrate, PH EUR ZINC ACETATE DIHYDRATE 98+% & ZINC ACETATE-2-HYDRATE TECHNICAL ZINC ACETATE-2-HYDRATE EXTRA PURE, U. S. P. ZINC ACETATE DIHYDRATE ACS REAGENT | [EINECS(EC#)]
209-170-2 | [Molecular Formula]
C4H10O6Zn | [MDL Number]
MFCD00066961 | [Molecular Weight]
219.51 | [MOL File]
5970-45-6.mol |
Chemical Properties | Back Directory | [Appearance]
Colourless or white efflorescent crystals with a f | [Melting point ]
100 °C
| [Boiling point ]
242-4°C | [density ]
1.84
| [storage temp. ]
Store at RT. | [solubility ]
430g/l | [form ]
Solid | [color ]
White | [Specific Gravity]
1.84 | [Odor]
Acetic acid odour | [PH]
6.0-8.0 (25℃, 50mg/mL in H2O) | [PH Range]
6 - 8 at 50 g/l at 25 °C | [Stability:]
Stable. Incompatible with alkalies, strong oxidizing agents. | [Water Solubility ]
430 g/L (20 ºC) | [Merck ]
14,10128 | [BRN ]
3732513 | [InChIKey]
BEAZKUGSCHFXIQ-UHFFFAOYSA-L | [LogP]
-0.285 (est) | [CAS DataBase Reference]
5970-45-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Zinc acetate dihydrate(5970-45-6) | [EPA Substance Registry System]
5970-45-6(EPA Substance) |
Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
R22:Harmful if swallowed. R36:Irritating to the eyes. R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S60:This material and/or its container must be disposed of as hazardous waste . S61:Avoid release to the environment. Refer to special instructions safety data sheet . S36:Wear suitable protective clothing . | [RIDADR ]
UN 3077 9/PG 3
| [WGK Germany ]
3
| [RTECS ]
ZG8750000
| [TSCA ]
No | [HazardClass ]
9 | [PackingGroup ]
III | [HS Code ]
29152900 | [Toxicity]
LD50 orally in rats: 2.46 g/kg (Smyth) |
Hazard Information | Back Directory | [Chemical Properties]
Zinc acetate dihydrate Zn(C2H3O2)•2H2O is a Colourless or white efflorescent crystals; faint acetic acid odor; astringent taste; monoclinic crystals; density 1.735 g/cm3; loses water at 100°C; decomposes at 237°C; readily dissolves in water, 43g/100 mL at 20°C; soluble in alcohol.
| [Chemical Properties]
Zinc acetate occurs as white crystalline, lustrous plates with a faint
acetic odor and an astringent taste. | [Production Methods]
Zinc acetate is synthesized by reacting zinc oxide with glacial acetic
acid, with subsequent crystallization, separation by centrifugation,
and drying and milling of the crystals. No organic solvents are used
during the synthesis. | [General Description]
Structure of zinc acetate dehydrate is monoclinic with unit cell dimensions a=14.50, b=5.32 and c=11.02?. | [Pharmaceutical Applications]
Zinc acetate has been used as an excipient in a variety of
pharmaceutical formulations including topical gels, lotions, and
solutions, and subcutaneous injections. It has also been investigated
for use in an oral controlled-release formulation for water-soluble
drugs in combination with sodium alginate and xanthan gum.
Therapeutically, zinc acetate has been used in oral capsules for
the treatment of Wilson’s disease. Zinc acetate has also been
demonstrated to be effective as a spermicide in vaginal contraceptives. | [Safety]
Zinc acetate is used in topical pharmaceutical formulations and
subcutaneous injections, where it is generally regarded as relatively
nontoxic and nonirritant when used as an excipient. However, zinc
acetate is poisonous by intravenous and intraperitoneal routes; it is
also moderately toxic following oral consumption.
LD50 (mouse, IP): 0.108 g/kg
LD50 (mouse, oral): 0.287 g/kg
LD50 (rat, IP): 0.162 g/kg
LD50 (rat, oral): 0.794 g/kg | [storage]
Zinc acetate loses water of hydration above 100℃. Zinc acetate
should be stored in an airtight container in a cool, dry, place. | [Purification Methods]
It crystallises (in poor yield) from hot water or, better, from EtOH. [Beilstein 2 III 193, 2 IV 114.] | [Incompatibilities]
Zinc acetate is incompatible with oxidizing agents, zinc salts, alkalis
and their carbonates, oxalates, phosphates, and sulfides. | [Regulatory Status]
Included in the FDA Inactive Ingredients Database (SC injections;
topical lotions and solutions). Included in medicines licensed in the
UK. |
Questions and Answers (Q&A) | Back Directory | [Uses]
Zinc acetate is used as a mordant in dyeing textiles; in preserving wood; in manufacturing glazes for painting on ceramics; and as an analytic reagent in measuring albumin, tannin, and phosphate. Other uses are as a crosslinking agent for polymers; and as a supplement in food. The compound is used in medicine as an astringent.
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